A sports medicine physician and public health scientist, Hoeg first gained attention during the pandemic as a critic of masking, school closures, vaccine mandates and other government measures. She co-wrote papers with other medical contrarians who would go on to join the Trump administration, including Makary and Prasad.

Like Makary and Prasad, Hoeg also frequently expressed her opinions in blog posts and podcasts, including one titled “Vaccine Curious.” The podcast discussed a number of discredited ideas, including that mRNA vaccines may contain harmful DNA contaminants.

A Danish American citizen, Hoeg was instrumental in the Trump administration’s recent effort to drop a number of federally recommended shots for children, including those for the flu and hepatitis B at birth. Those changes have been temporarily blocked by a federal judge in Boston, though the administration plans to appeal the decision.

At the FDA, Hoeg led an “initial analysis” of vaccine injuries that linked COVID-19 shots to 10 reported deaths in children — without providing the supporting evidence. The findings were discussed in an internal memo Prasad sent to staffers last November, though the FDA has not formally announced the findings or explained how they were developed.

Officials from the FDA and the Centers for Disease Control and Prevention have previously concluded that serious side effects from the vaccines are extremely rare.

More recently, Hoeg was involved in the agency’s review of a formal petition to add bold new warnings to antidepressant drugs about unproven pregnancy risks, including fetal abnormalities that could lead to autism and other disorders.

In March, she attempted to hire the author of the petition to serve as a senior adviser at the FDA, according to people familiar with the situation. The matter raised concerns among some agency staff because Hoeg had repeatedly referred to the person as a friend, according to the people who spoke to the AP on the condition of anonymity to discuss confidential FDA matters.